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superresolution illumination microscope n-sim  (Nikon)


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    Nikon superresolution illumination microscope n-sim
    Superresolution Illumination Microscope N Sim, supplied by Nikon, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/superresolution illumination microscope n-sim/product/Nikon
    Average 90 stars, based on 1 article reviews
    superresolution illumination microscope n-sim - by Bioz Stars, 2026-05
    90/100 stars

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    structured illumination superresolution microscope (n-sim  (Nikon)
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    Nikon structured illumination superresolution microscope (n-sim
    SIM enables precise imaging of AβOs bound to spines. SIM was used to determine the binding of AβOs to primary hippocampal neurons, using the N-SIM <t>superresolution</t> <t>microscope</t> with a lateral resolution at 100× of ∼100 nm, compared with the more typical 400 nm of most microscopes. Primary hippocampal cells, cultured for 19 d, were treated with 100 nM AβOs for 1 h and immunolabeled with anti-TuJ (green) and NU4 (magenta).
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    SIM enables precise imaging of AβOs bound to spines. SIM was used to determine the binding of AβOs to primary hippocampal neurons, using the N-SIM superresolution microscope with a lateral resolution at 100× of ∼100 nm, compared with the more typical 400 nm of most microscopes. Primary hippocampal cells, cultured for 19 d, were treated with 100 nM AβOs for 1 h and immunolabeled with anti-TuJ (green) and NU4 (magenta).

    Journal: Molecular Biology of the Cell

    Article Title: Neuroprotective astrocyte-derived insulin/insulin-like growth factor 1 stimulates endocytic processing and extracellular release of neuron-bound Aβ oligomers

    doi: 10.1091/mbc.E17-06-0416

    Figure Lengend Snippet: SIM enables precise imaging of AβOs bound to spines. SIM was used to determine the binding of AβOs to primary hippocampal neurons, using the N-SIM superresolution microscope with a lateral resolution at 100× of ∼100 nm, compared with the more typical 400 nm of most microscopes. Primary hippocampal cells, cultured for 19 d, were treated with 100 nM AβOs for 1 h and immunolabeled with anti-TuJ (green) and NU4 (magenta).

    Article Snippet: N-SIM images were captured on a Nikon N-SIM Structured Illumination superresolution microscope.

    Techniques: Imaging, Binding Assay, Microscopy, Cell Culture, Immunolabeling